I love making and working with Cleveland maps! I actually used to have all 27 neighborhoods lined out on Microsoft Streets & Trips, but now use Mac so I don't access those files anymore. I have resorted to a gigantic map by Rand McNally of Cuyahoga County, which I had laminated and mounted. I then use dry erase marker to draw lines and use tacks to mark points. I'd be interested to give you info. if you like regarding anything.
One of the most enjoyable things is trying to find a way to not only track the 27 neighborhoods but also some of the neighborhoods in the inner rings: Cleveland Heights in particular. Cedar-Fairmount and Coventry for example are neighborhoods, but it's not so easy to draw the boundaries. When you factor in the new "Forest Hills Historic District" it gets trickier since it lies in both neighborhoods. All in all it's fun to work on and over time by not only plotting maps but driving/walking through the areas, you learn where real boundaries are, such as main artery roads and whatnot. As for Little Italy, that is within University, and Quadrangle is the official title (or at least it was) of CSU/Tri-C/St. Vincent. Some of the neighborhoods and districts are intertwined, such as MidTown, AsiaTown, Artists Quarter's, and so forth. As for even further micro-neighborhoods, some exist, some no longer exist, such as Poznan and the aforementioned Big Italy. Again, if you'd like to know more, just ask, or you're welcome to stop by and see my map - it's in my office downtown.