If all of these yuppie apartment complexes hadn't been built, some landlords would have been motivated to fully rehab their buildings and the increased UC student population would now be renting homes deeper into Corryville, Mt. Auburn, Avondale near the zoo, and streets along McMicken like Hastings and Tafel.
I think those neighborhoods (except maybe for Corryville) need stronger connections to campus & Clifton Heights for that to happen.
Take Mt Auburn and the streets around Auburn Ave. for example. The area feels completely cut off from campus. This is because McMillan and Taft are high traffic, high speed one way streets that have a moat effect. Then the University Plaza lot forms another barrier separating it from Corryville. And there is a steep up and down dip in elevation right around Vine St. to further the effect. It may not take the Uptown Five https://dl.dropboxusercontent.com/u/70250228/The%20Uptown%20Five%2009302014.pdf
to reconnect Mt Auburn; I think there's other things you could do (more pedestrian friendly two way streets, get University Plaza right) to reconnect it. (I see lots of potential down Auburn Ave around Jackson Hill Park. I really like the flatiron style currently abandoned building down by the Sycamore St. intersection.) Strong connections are so important- I think it's telling that now demolished Glencoe-Auburn Place was known as the Glencoe "Hole"- limited access in and out, tucked away in the corner and forgotten.
To go completely off topic you have an analogous situation where Betts-Longworth and the lower West End is cut off from OTR by Central Parkway, the electric substation, and Channel 48 studio/parking garage superblock. Although that area is doing well and has more of a "quiet oasis" feel which I really, really like, it would probably have more buzz and be a candidate for more infill if it were better connected.